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Projects
Current:
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2R01 MH064769-06A1 Luby (PI)
Funded by the NIMH from 12-19-07 to 11-30-2012.
Preschool Mood Disorders Developmental Continuity and School Age Outcomes Study
– This project is a continuation of the 1 R01: Validation of Preschool
Depressive Syndromes. It follows this preschool population into school age and
early adolescents for another five-year period to investigate the nosology and
longitudinal course of preschool depression.
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R34 MH080163 Luby (PI)
Funded by the NIMH from 10/1/07 to 9/30/10.
Parent Child Interaction Therapy – Emotional Development (PCIT-ED) Study
– Early Intervention in Depression: Dyadic Emotion Development Therapy for
Preschool Children - This project modifies and expands a previously validated
parent-child therapy (Parent Child Interaction Therapy, PCIT) for use in
preschoolers with symptoms of depression. The modified therapy, Parent Child
Interaction Therapy - Emotion Development (PCIT-ED) incorporates the
enhancement of emotion development skills. The study will test this newly
developed parent-child psychotherapy in preschoolers with depressive symptoms
and compare it to an education control condition.
The PCIT-ED study is currently recruiting families who have particularly sad or
irritable preschoolers for a psychotherapy treatment study. Potentially
eligible preschoolers (age 3 - 5years 11 mos) may have the following kinds of
moods and behaviors: often sad and/or plays things with sad themes, cries a
lot, is grouchy or irritable a lot of the day, is hard on him/herself, seems to
have low self esteem, reacts to mistakes with a excessive guilt, among other
things. Click here to open a printable
brochure for this study. If interested, call Jennifer Pautsch, LPC at (314)
286-2671.
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Luby (PI)
Funded by NARSAD from 9/15/04 to 9/14/06 (no cost extension).
Neuroimaging of Melancholic Depressed Preschoolers at School Age - The
aim of this study is to conduct follow-up psychiatric assessments and magnetic
resonance imaging (MRI) in an ascertained group of children previously studied
at preschool age with a known melancholic depression.
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Luby (PI) & Barch – (Co-PI)
Funded by the CHADS Coalition from 2008 to 2010.
Functional Neuroimaging in a Depressed Preschool Population Pre and Post Treatment – The goal of the proposed study is to conduct functional
imaging in depressed 3-6 year old children who are participating in an NIMH
funded randomized controlled trial of a parent-child developmental therapy
treatment or education control condition. The imaging study will conduct
functional neuroimaging in very young depressed children pre and post
treatment.
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